This building was that of the University of Valencia, where there were some faculties until a few years ago. Originally from the end of the 15th century, it reached its current configuration with the reform of 1839, carried out by Timoteo Calvo after the damage of the War of Independence, and other later ones; until the project of Luis Carratalá and Antonio Escario (1997-1999) is carried out. In 1840 the exterior facade was rebuilt following the neoclassical model projected by Antonio Martorell in 1793.

The university auditorium dates from the 17th century. The neoclassical chapel, from the 18th century, and the library also stand out.

The courtyard of the rectory dates from 1842, and was also designed by the architect Timoteo Calvo.

In 1954, Javier Goerlich demolished houses that dominated the Plaza del Colegio del Patriarca, leaving the building occupying the entire block.
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